| abstract |
The present invention relates to composition for the treatment of diseases that involve cell proliferation. The invention also relates to a method for the treatment of said diseases, which comprises the co-administration of a compound 1 of formula (I) wherein the groups L, R1, R2, R3, R4 and R5 have the meanings given in the claims and in the descriptive part, optionally in the form of their tautomers, racemates, enantiomers, diastereoisomers and mixtures thereof and, optionally, in the form of their salts by the addition of acids, solvates, hydrates, polymorphs, physiologically functional derivatives or pharmacologically acceptable prodrugs. , and an effective amount of an active compound 2 and / or co-treatment with radiation therapy, in a relationship that provides an additive and synergistic effect, and to the combined use of a compound 1 of formula (I) and an effective amount of an active compound 2 and / or radiotherapy, for the manufacture of corresponding pharmaceutical combination preparations. (see formula). |