| abstract |
A compound, represented by formula (1) or an enantiomer, diastereoisomer or tautomer thereof: (see formula I) wherein A or B is nitrogen and the other B or A is O and the radicals R1, R2, R3, R5 , R6, R7, R9 and R10 are as defined herein, or a salt, ester or derivative thereof, as viral polymerase inhibitors. The compound is used as an RNA-dependent RNA polymerase inhibitor, particularly viral polymerases within the Flaviviridae family, more particularly VRO polymerase. |