abstract |
The present invention relates to novel ligands for the subgroup D2 and D3 of dopamine receptors of formula (I): wherein R 1 and R 2 independently represent a substituent selected from the group consisting of hydrogen, alkyl, aryl, cycloalkyl, aroyl, or R 1 and R 2 may form a heterocyclic a ring with an adjacent nitrogen atom; X represents an oxygen or sulfur atom; n is an integer from 1 to 2; and / or their geometric isomers and / or stereoisomers and / or diastereomers and / or salts and / or hydrates and / or solvates, the process for their production, the pharmaceutical compositions containing them and their use in the treatment and / or prevention of conditions requires modulation of dopamine receptors. |