Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8654b3f7649d7b5ff5036530a378d2a8 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C337-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-175 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-53 |
filingDate |
2020-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a952701c01072e70ffe9d24a9f3c873d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_044923345c4202dba7499c23522054ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f4e4075f6371bb21a43bcd34fc9d80f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dcfcd13727b2fbb659b5b923c4c6d0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8346689a4a71c0c3c114423fd159b7d6 |
publicationDate |
2022-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
MD-4764-C1 |
titleOfInvention |
Dibromo{methyl-N-(prop-2-en-1-yl)-2-[1-(pyridin-2-yl)ethylidene]hydrazine-carbimidothioate-N,N,S}copper compound inhibiting human rhabdomyosarcoma cell proliferation |
abstract |
The invention relates to chemistry and medicine, namely to a biologically active coordination compound of the class S-alkylisothiosemicarbazonates of transition metals and can be used in medicine for the prevention and treatment of rhabdomyosarcoma. 1-yl)-2-[1-(pyridin-2-yl)ethylidene]hydrazine-carbimidothioate-N,N,S}copper of the formula: inhibiting the proliferation of RD human rhabdomyosarcoma cells. The result of the invention is the synthesis of a copper coordination compound, which inhibits the proliferation of RD human rhabdomyosarcoma cells 13.6 times more actively than its structural analogue. |
priorityDate |
2020-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |