abstract |
The invention relates to the 1,4-benzothiazepine derivatives represented by the structural formula (I) :( I) where R is COOH, and to pharmaceutically acceptable salts thereof. Described is the use of said compounds for treating the conditions, disorders and diseases associated with The invention also discloses pharmaceutical compositions containing the described compounds and their use for treating diseases and conditions associated with RyRs, in particular cardiac, osteomuscular and nervous system disorders. central. |