http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MD-4452-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8654b3f7649d7b5ff5036530a378d2a8 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-175 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 |
| filingDate | 2016-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dcfcd13727b2fbb659b5b923c4c6d0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bbc84a2f24e5e5090849299990b3570 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9bce0d5085f040138b9cb9ff8fd9313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f4e4075f6371bb21a43bcd34fc9d80f |
| publicationDate | 2016-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MD-4452-B1 |
| titleOfInvention | Use of N- (2,4-dimethylphenyl) -2- (2-hydroxybenzylidene) -hydrazincarbotioamide as an inhibitor of Candida albicans fungal proliferation |
| abstract | The invention relates to chemistry and medicine, in particular to the use of an organic biologically active compound of the thiosemicarbazone class, which exhibits high bacteriostatic and bactericidal activity against Candida albicans and can be used in medicine and veterinary medicine for the prevention and treatment of mycoses. The invention consists in the use of N- (2,4-Dimethylphenyl) -2- (2-hydroxybenzylidene) -hydrazinecarbothioamide of the formula: as an inhibitor of the growth and reproduction of fungi such as Candida albicans. Moreover, this thiosemicarbazone p at the same time, it shows 2 times higher bacteriostatic antimicrobial activity against Staphylococcus aureus and 4 ... 17 times higher against Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa, compared to methyl N '- [(2-hydroxynaphthalen-1- il) methylidene] -N- (prop-2-en-1-yl) -hydrazidocarbimidothioate. |
| priorityDate | 2016-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.