http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MD-225-C2

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filingDate 1994-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_726f59a2ef6dae98b813c755876fc4cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_019bb8b7b61bd990252f16a42500bcf8
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publicationDate 1995-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MD-225-C2
titleOfInvention The method of obtaining a hydrated crystalline form of the sodium salt of 3-acetoxymethyl 7- (2- (2-amino-4-thiazolyl) -2-methoxyiminoacetamido) cef-3-em-4-carboxylic acid syn-isomer
abstract The invention relates to a process for obtaining antibiotics from the group of cephalosporins, namely a novel crystalline hydrated form of the sodium salt of 3-acetoxymethyl-7- [2- (2-amino-4-thiazolyl) -2-methoxyiminoacetamido The object of the invention is to obtain a cephalosporin antibiotic in a novel crystalline form with increased stability and low hydrophilicity. The process provides for the interaction of 3-acetoxymethyl-7 acid. - [2- (2-Amino-4-thiazolyl) -2-2-methoxyiminoacetamido] -cef-3-em-4-carbonic acid, its synisometry or hydrate, ethanolic solvate, formate solvate or mixture of hydrate and ethanolic solvates or formiatically, in methanol medium with the sodium salt of an organic acid, selected from the group, consisting of sodium acetate, sodium ethylhexanoate and sodium diethyl acetate, sodium ethylhexanoate and sodium diethyl acetate. with formula I, which was formed It is separated and, if necessary, converted to the crystalline sodium salt, which does not contain methanol, and it is hydrated either directly or directly to the crystalline methanolic solvate of the sodium salt.
priorityDate 1977-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 33.