| abstract |
The present invention relates to a compound of formula 1, 2 or 3: Formula 1 \ tab Formula 2 Formula 3 where A is N or -CR0--, where R0 is hydrogen, C1-C6 linear or branched alkyl, etc., Z is -CRe-- or -N--, where Re is hydrogen, C1-C6 linear or branched alkyl, etc .; R1 is hydrogen, C1-C6 linear or branched alkyl, etc .; R2 independently represents hydrogen or C1-C6 linear or branched alkyl; R3 and R4 independently represent hydrogen, C1-C6 linear or branched alkyl, etc .; R5 and R6 independently represent hydrogen or C1-C6 linear or branched alkyl, etc .; R8 is hydrogen, C1-C6 linear or branched alkyl, etc .; R9 and R10 independently represent hydrogen or C1-C6 linear or branched alkyl, etc .; Q is --CO--, - (CH2) q--, - (CHRs) q-- or - (CRsRt) q--, where Rs and Rt independently are C1-C6 linear or branched alkyl, aryl, alkylaryl, heteroaryl or alkyl heteroaryl; where q is 0, 1, 2 or 3; and where n represents 0, 1, 2, 3, 4 or 5; or its pharmaceutically acceptable salt, to compositions containing such compounds; and the use of such compounds in the treatment of various diseases, in particular diseases that are affected or that are mediated by the androgen receptor. |