| abstract |
The present invention relates to compounds of formula (i) wherein q is selected from o or s; r1 is a non-aromatic heterocyclic group comprising at least one cyclic nitrogen atom, r1 being attached to the sulfur atom of the sulphonylurea group by a cyclic carbon atom, r1 possibly being substituted; and r2 is an a-substituted cyclic group, wherein r2 may be optionally substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising said compounds, and to the use of these compounds in the treatment and prevention of medical disorders and diseases, more particularly by nlrp3 inhibition. |