abstract |
The present invention provides aqueous ophthalmic compositions in solution form comprising hexanoic acid, 6- (nitrooxy) -, (1s, 2e) -3 - [(1r, 2r, 3s, 5r) -2 - [(2z ) -7 - (ethylamino) -7-oxo-2-hepten-1-yl] -3,5-dihydroxycyclopentyl] -1- (2-phenylethyl) -2-propen-1-yl ester and macrogol 15 hydroxystearate as only solubilizing agent, and a method for their preparation. |