| abstract |
The present invention relates to novel (aza) pyridopyrazolopyrimidinones and substituted indazolopyrimidinones, processes for their preparation, the compounds for use alone or in combination in a method for the treatment and / or prophylaxis of diseases, in particular for the treatment of and / or prophylaxis of short and recurrent bleeding in patients with or without underlying hereditary or bleeding bleeding disorders, the bleeding being associated with a disease or surgery selected from the group consisting of menorrhagia, postpartum hemorrhage, hemorrhagic shock, trauma, surgery, transplantation, stroke, liver disease, hereditary quincke edema, nosebleed, and synovitis and cartilaginous lesions following hemarthrosis . |