http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MA-37729-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2866b0c055618e47347e03d9bcf9f540 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-534 |
| filingDate | 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6183e0e7ecfc0d106d6f77b644b527e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6af1f0f8c6d5d1cbbb23546319b43a0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d9c838b141dd9aa4496e5fc343718bf |
| publicationDate | 2016-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MA-37729-A1 |
| titleOfInvention | Pharmacological composition of the essential oils of mint lemon grass, origon, thyme, bitter orange and palmarosa with antibacterial effect on the aggregatibacter actinomycetemcomitans |
| abstract | Chemical composition: the chemical analysis of the essential oil studied revealed the following major constituents: r (+) - pulegone (71.48%) and carvone (5.66%) (table 1). Antibacterial activity diffusion test in well: after the incubation period (48h), zones of bacterial growth inhibition on agar are obtained and measured by calipers (Table 2). However, no inhibition halo is obtained for the negative controls (tween 80 pure and diluted 10%). Regarding the growth control used, a bacterial growth in the form of a film covering the agar is obtained. The average diameter of the zones of inhibition induced by doxycycline (22.67 ± 1.15 mm) is significantly smaller than that produced by the essential oil tested in the pure state (39 ± 1.00 mm). The diameters of the zones of inhibition observed for the essential oil of mint pulegium l. in the crude state, showed values greater than 20 mm (Table 2), reflecting a high sensitivity of the strain aggregatibacter actinomycetemcomitans clone ip2 to the oil studied.Microdilution test: the recorded values of cmi, cmb and cmb / cmi ratio are represented in Table 3. The cmi (0.3%) and the cmb (0.6%) obtained testify to an effective antibacterial activity of the essential oil mentha pulegium l. In the study deshapiro et al. 1994, a similar cmi value (0.3%) on aa (non-ipz clone) was found for mentha piperita, which is of the same species (mentha) as mentha pulegium, which support our results. The ratio cmb / cmi obtained is less than 4, which gives information on the nature of the antibacterial effect of the essential oil tested which thus proves bactericidal. |
| priorityDate | 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.