| abstract |
The present invention relates to a solid preparation in which the weight variation is suppressed, a solid preparation in which the active ingredient is stabilized and a method of stabilizing it. The invention also relates to a solid preparation containing (1) an active ingredient, (2) D-mannitol and (3) and an alkaline earth metal salt selected from magnesium aluminometasilicate and calcium silicate. The invention also relates to a method of stabilizing the active ingredient which comprises adding an alkaline earth metal salt selected from magnesium aluminometasilicate and calcium silicate. |