| abstract |
Compounds of formula (i) wherein: r1 represents a heteroaryl or heterocyclic group optionally substituted by one or more atoms or groups; x represents from 1 to 4 identical or different substituents chosen from hydrogen, halogen, (c1-c10) alkyl, (c1-c10) alkoxy, nrarb, nitro, cyano, the group (c1-c10 ) alkyl which may be optionally substituted by one or more groups selected from halogen, (C1-c10) alkoxy, (C1-c10) haloalkoxy, nrarb or hydroxyl; r represents in position 3, 5, 7 or 8 of the imidazo [1,2 -?] pyridine of 1 to 4 identical or different substituents of each other selected from a hydrogen, a halogen, (c1-c10 ) alkyl, halo (C1-C10) alkyl, (C1-C10) alkoxy; r2 and r3 represent, independently of each other, a hydrogen atom, a (C1-C10) alkyl group, optionally substituted by an RF group, or an optionally substituted aryl group; r4 represents: a hydrogen atom, a (C1-C10) alkyl group, optionally substituted with a rf group; an aryl group, optionally substituted, in the form of a base or an addition salt with an acid. Therapeutic use and synthesis method. |