http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MA-30502-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_132aa5ddba376cda52c2bedb26765245 |
| filingDate | 2008-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d8dfdbfb7fa83bb75bd5a2a0d2ca8f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76c32c2556cb5972ea0c04bfb3b88eda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_191ed271ad9c730b08538365d8938c73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_785c6c1b8ea3dece7a3e2db2d2b21ecd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3ebf93bca6439c296dced50e3e86d06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd07d89ae6002a77f4c22826ae4ec9cf |
| publicationDate | 2009-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MA-30502-B1 |
| titleOfInvention | CRYSTALLINE FORMS OF 11? - (4-ACETYLPHENYL) -20,20,21,21,21-PENTAFLUORO-17-HYDROXY-19-NOR-17α-PREGNA-4,9-DIEN-3-ONE. |
| abstract | The present invention relates to crystalline forms of 11? - (4-acetylphenyl) -20,20,21,21,21-pentafluoro-17-hydroxy-19-nor-17 (alpha) -pregna-4,9-dieno 3-one. In particular, the invention relates to two crystalline asolvated / anhydrous forms of this compound, polymorphs I and II. The present invention, however, also relates to crystalline solvates, for example 11β- (4-acetylphenyl) -20,20,21,21,21-pentafluoro-17-hydroxy-19-nor methanol and ethanol solvates. -17 (alpha) -pregna-4,9-dien-3-one as precursors for the preparation of these two polymorphs I and II. Processes for preparing polymorph I by displacement crystallization or stirring extraction are described. The choice of the last solvent before the formation of the asolvate can be carried out using the differences in the purification behavior of the different solvates of 11? - (4-acetylphenyl) -20,20,21,21,21-pentafluorone? 17-hydroxy-19-nor-17 (alpha) -pregna-4,9-dien-3-one. The polymorph I according to the invention is particularly suitable for the preparation of medicaments. |
| priorityDate | 2006-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.