| abstract |
The invention relates to tricyclic N-heteroarylcarboxamide derivatives containing a benzimidazole unit, of general formula (I) in which A represents, with the CN bond of the benzimidazole unit to which it is fused, a monocyclic heterocycle or a monocyclic heteroaryl of 4 7-membered ring containing from one to three heteroatoms selected from O, S or N, including the nitrogen atom of the benzimidazole moiety; P represents an 8-, 9-, 10- or 11-membered bicyclic heterocycle or bicyclic heteroaryl comprising from 1 to 6 heteroatoms selected from N, O and S; R 1 represents from one to four atoms or groups, identical or different; Y represents an oxygen or sulfur atom; R2 represents a hydrogen atom, a halogen atom, a C1C6-alkyl, C3-C7-cycloalkyl, C3-C7-cycloalkyl-C1-C3-alkylene, C1C6-fluoroalkyl or C1C6-alkoxy group; R3 represents from one to three atoms or groups, identical or different; in the form of a base or an acid addition salt, as well as a hydrate or solvate state. The invention also relates to a process for preparing the compounds and their therapeutic application. |