| abstract |
The invention relates to a solid pharmaceutical composition (such as a solid dosage form) comprising a delivery agent and wet heparin. The inclusion of wet heparin causes, in the solid pharmaceutical composition, much more than a non-wetted heparin, increased administration of heparin. Without any connection with a particular theory, the inventors believe that because the wet heparin polymer chain is already an "open" form, while the non-wetted heparin is not, less wet heparin is decomposed in the gastrointestinal tract and is more easily absorbed into the stomach. |