| abstract |
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChRs), the activation of nAChRs and the treatment of diseases associated with a nicotinic acetylcholine receptor defect or dysfunction, in particular in the brain. In addition, the invention relates to novel compounds, for example indoles, 1H-indazoles, 1,2-benzisoxazoles and 1,2-benisothiazoles, which act as ligand for the nAChR (alpha) 7 subtype, processes for the preparation of these compounds, compositions containing these compounds and methods of use thereof. |