| abstract |
The present invention encompasses the structures of the formula: or the non-toxic pharmaceutically acceptable salts derived therefrom where: W represents substituted or unsubstituted phenyl; X is hydrogen, hydroxy or light alkyl; T is hydrogen, halogen, hydroxy, nitro, amino or alkyl; R3 is hydrogen or an organic group; R4 is hydrogen or a substituted or unsubstituted organic substituent; R5 and R6 represent organic and inorganic substituents; and n is 1, 2,3 or 4, the compounds of which are agonists, antagonists or inverse agonists very selective for the GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for the brain receptors GABA. These compounds are useful for the diagnosis and treatment of anxiety, sleep and epilepsy disorders, overdoses of benzodiazepine drugs and to improve memory. |