abstract |
The invention relates to the field of biochemistry and medicine, particularly to 5-(4-chlorobuthyl)-pyrano[2,3-d]pyrimidin-2,4,7(3H)-trione and 5-alkyl-2-thioxo-1H-pyrano[2,3-d]pyrimidin-4,7-diones as ligands of hydroxycarboxylic acid (HCA) class receptors (including niacin group), useable in medicine for prevention and treating of diseases of lipids, cholesterol and carbohydrates metabolism as well as atherosclerotic and inflammatory processes. |