http://rdf.ncbi.nlm.nih.gov/pubchem/patent/LV-14266-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7d7c4562e8e9edb70e0f2047e6da705 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C55-10 |
| filingDate | 2009-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a88e4636ba37c8d7965394dd9d9adaaa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_830542707a3a1611019c8e4d842c2c04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bda55ac9df5717fa4560c9dbedb5da7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c55f7a0151208c3f6ee8f51a030a6b40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac77ac821a0fc5123ec91bd9d9e043d2 |
| publicationDate | 2011-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | LV-14266-B |
| titleOfInvention | New nick ī nsk ā bes & meldonia therapeutic ā |
| abstract | The present invention comprises a synergistic combination of nicotinic acid and meldonium characterized by increased efficiency in treating metabolic-related disorders, including dyslipidemia, hyperlipidemia, atherosclerosis, coronary heart disease as chosen from the group of angina pectoris and myocardial infarction, transient and permanent ischemic attack including cerebrovascular accident and stroke and peripheral arterial occlusive disease, and by reduced flushing effect and/or increase of blood glucose levels, comprising as active ingredients nicotinic acid or pharmaceutically acceptable salt thereof and meldonium or pharmaceutically acceptable salt thereof, effective for said purpose. Such combination comprises nicotinic acid or pharmaceutically acceptable salt thereof in dose at least about 50 - 500 mg and meldonium or pharmaceutically acceptable salt thereof in dose at least about 50 - 500 mg in a pharmaceutical composition form, comprising the active ingredients in association with a pharmaceutically acceptable diluent or carrier. Moreover, a method of treating metabolic-related disturbances in a subject in need of the same is provided, comprising the step of simultaneously or sequentially administering to the said subject both nicotinic acid and meldonium as separate pharmaceutical compositions, the first composition comprising about 50 - 500 mg of nicotinic acid or pharmaceutically acceptable salt thereof and the second composition comprising about 50 - 500 mg of meldonium or pharmaceutically acceptable salt thereof in association with a pharmaceutically acceptable diluent or carrier. |
| priorityDate | 2009-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.