abstract |
Three component method for preparation of 4-(2-chlorophenyl)-2-[2-(1,3-dioxo-1,3-dihydroizoindol-2-yl)-ethoxymethyl]-6-methyl-1,4-dihydropyridin-3,5-dicarboxylic acid 3-ethyl-5-methyl ester (phtalimidoamlodipine) by making use ionic liquids as promotors was described. |