http://rdf.ncbi.nlm.nih.gov/pubchem/patent/LV-13677-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B63-00 |
| filingDate | 2007-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c75f07838a8a23c74523afb6436a2ab3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8471d45fa9c1955864c3972769c6a753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a0d1d1e66cb9fbfa08d851f02e975b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07a691965dbbf09af93f80a97787406e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02a02a19757b09826fc9edcc59ae2d0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e34e0cc61bc24ab88199ab845df352c |
| publicationDate | 2008-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | LV-13677-B |
| titleOfInvention | Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base |
| abstract | The present invention relates to the crystalline base of the well known antidepressant drug escitalopram, S-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile, formulations of said base, a process for the preparation of purified salts of escitalopram, such as the oxalate, using the base, the salts obtained by said process and formulations containing such salts, and a process for the preparation of purified escitalopram free base or salts of escitalopram, such as the oxalate, using the hydrobromide, the salts obtained by said process and formulations containing such salts. Finally the present invention relates to an orodispersible tablet having a hardness of at least 22 N and an oral-disintegration time of less than 120 s and comprising an active pharmaceutical ingredient adsorbed onto a water soluble filler wherein the active pharmaceutical ingredient has a melting point in the range of 40-100 °C, as well as a method for making such an orodispersible tablet. |
| priorityDate | 2005-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.