| abstract |
The invention relates to the use of imidazo[1,5-a]-pyrido[3,2-e]-pyrazinones of formula (1) as inhibitors for phosphodiesterase 5 for the therapy of erectile dysfunction (impotence). The invention also relates to the use of imidazo[1,5-a]-pyrido[3,2-e]-pyrazinones of formula (1) as dual inhibitors of phosphodiesterase 3 and of phosphodiesterase 5 for the therapy of heart failure, pulmonic hypertonia and vascular diseases which are accompanied by insufficient blood supply. The invention further relates to a method for making the same. |