abstract |
aP2 inhibiting compounds are provided having formula (I) wherein R1, R2 ,R3 , R4 , X-Z and (a) are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing such aP2 inhibitor or a combination of such aP2 inhibitor and another antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin. |