http://rdf.ncbi.nlm.nih.gov/pubchem/patent/LU-500612-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44ae178fe5ea1fd193b8e5e1baf1ab3b |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 |
filingDate | 2021-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd89c8d97d8165bde769a74e3cccf6af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10b1dd247fa414f2650cebec7dc8ebab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11e5165ccb01268d88e9b581fe0f33cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61615d94c02b05fcbc072f8a26e5a2cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa65f6448033b0062147aab58aa2723b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d1722737e885759296fdf7e1f43dcab |
publicationDate | 2022-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | LU-500612-B1 |
titleOfInvention | Aptamer qq-4 targeting human high-invasive choroidal melanoma and application thereof |
abstract | The present application provides an aptamer QQ-4 targeting human high-invasive choroidal melanoma and application thereof. Nature characterization of the aptamer QQ-4 and identification of the target molecules are helpful to discover tumor markers for diagnosis and targeted therapy of choroidal melanoma. The prepared aptamer is capable of specifically recognizing high-invasive choroidal melanoma cells and choroidal melanoma tissues, has high affinity, no immunogenicity and small molecular weight, and can be chemically synthesized in vitro; different parts of the aptamer are easily modified and substituted. Meanwhile, the sequence of the aptamer is stable, thus it can be stored and labeled conveniently. When human choroidal melanoma cells are detected using the aptamer of the disclosure, the operation is simpler and rapider. Furthermore, the synthesis cost of the aptamer of the disclosure is lower than that of antibody preparation, with short cycle and good reproducibility. |
priorityDate | 2021-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.