Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44ae178fe5ea1fd193b8e5e1baf1ab3b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 |
filingDate |
2021-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11e5165ccb01268d88e9b581fe0f33cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10b1dd247fa414f2650cebec7dc8ebab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7aefaee93dec9c0c8926f3620744a811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61615d94c02b05fcbc072f8a26e5a2cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5632b5e3cb33a78fa5927d80e7ea64c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a13a0f4a1821d3a7ad1c6206b38693ce |
publicationDate |
2022-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
LU-500610-B1 |
titleOfInvention |
Method and aptamer pq-6 for recognizing tumor target protein jup and application thereof |
abstract |
The disclosure provides a method and an aptamer PQ-6 for recognizing tumor target protein JUP and application thereof. The target protein JUP recognized by the aptamer PQ-6 is expressed on the surfaces of multiple tumors and associated with invasiveness of tumors, thus the ability of the aptamer PQ-6 to specifically recognize the JUP protein can be used for researches on multiple tumors. In addition, because of strong cell internalization, the aptamer PQ-6 can serve as a target vector to be coupled with an anti-tumor drug to construct a target drug delivery system, thereby achieving the target therapy of tumors while reducing the side effects brought by the non-target effect of a chemotherapeutic drug. |
priorityDate |
2021-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |