http://rdf.ncbi.nlm.nih.gov/pubchem/patent/LT-IP600-A

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38c981fa8340314d4a95cfa625cf4bf0
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57
filingDate 1993-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7efca6cfad9ce116de1f61b8670d0783
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publicationDate 1994-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber LT-IP600-A
titleOfInvention NEW PREGNANT SCALE STEROIDS, PHARMACEUTICAL COMPOSITION AND METHOD OF ADMINISTRATION
abstract The present invention relates to novel therapeutically active 21-aminosteroids having the formula @@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ @@@ as a substitute, an amino group substituted with a branched C4-8 alkyl, alkenyl or alkynyl group, or a C4-10 cycloalkyl group containing 1-3 rings which may contain a C1-3 alkyl group (s); or @ R 1 and R 2 together form a spiro-heterocyclic secondary amino group having up to 10 carbon atoms and which may contain at least one oxygen atom as an additional heteroatom; or one of R 1 and R 2 is an unsubstituted heterocyclic secondary amino group having from 4 to 7 carbon atoms, and the other is the above-mentioned primary amino group, the above-mentioned spiroheterocyclic secondary amino group, or a heterocyclic secondary amino group having from 4 to 7 C atoms with Cl -4-alkyl (s) substituted; and n is 1 or 2, @ and their addition salts, and the pharmaceutical composition comprising these compounds. In addition, the invention is also contemplated for the preparation of the above compounds. Compounds of formula (I) are antioxidant, especially lipid. peroxidation inhibitory effect, and therefore may be useful in treating the pathological effects of lipid peroxidation in mammalian, including human, organisms.
priorityDate 1992-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
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Total number of triples: 31.