| abstract |
The present invention describes the N4-modified cytidine nucleotides. The synthesis of N4-modified cytidine triphosphates and methods of using modified cytidine nucleotides as well as the use of the ciditin analogs provided for the synthesis of modified nucleic acids are provided. Nucleic acids can be composed of a combination of DNA, RNA, or DNA / RNA. One of the modified areas for the use of cytidine nucleotides is the selection of enzymes where the enzymes exhibit esterase, amidase, oxidoreductase, liazine, ligase or other enzymatic activity. |