abstract |
Azole derivatives, which have a general formula (I):<IMAGE>where A, Z, O, R1, X, Y, Z and q have indicated meanings, their extraction method, pharmaceutical preparations and the use of these compounds, as medical substances. The azole derivatives, which have a formula (I), in which the symbols, for example, have these meanings:R<1> - (C2-C10)-alkyl,Z - azote,X, Y - independently from one another, CR<2>,Z - -CH2-,q - 0 or 1,A - biphenyl residue, in which there is a substitute, for example, R<15>,R<2> - halogen or hydrate,R<15> - SO2-NH-CO-R<6> andR<6> - phenylare very effective antagonists of angiotensin-II-receptors. |