http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-980002009-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-24 |
filingDate | 1996-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1998-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-980002009-A |
titleOfInvention | Preparation of N-methyl-3 - [(4-trifluoromethyl) phenoxy] -3-phenylpropylamine |
abstract | The present invention relates to a novel process for the preparation of N-methyl-3 - [(4-trifluoromethyl) phenoxy] -3-phenylpropylamine which is used as a psychotropic drug, in particular as an antidepressant, Reacting the compound of formula (I) with an appropriate base in a suitable solvent at a low temperature, adding a compound of formula (I) and stirring at an appropriate temperature to prepare a compound of formula (II); A step of reacting a compound of formula (II) with a halogenating agent to produce a compound of formula (III); A step 3 of preparing a compound of formula (IV) from a compound of formula (III); Reacting a compound of formula (IV) with a compound of formula (VIII) in a suitable solvent and an appropriate base to give N-methyl-3 - [(4-trifluoromethyl) phenoxy] Amine and its hydrochloride salt. |
priorityDate | 1996-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.