http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-970061863-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-60 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-10 |
filingDate | 1996-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1997-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-970061863-A |
titleOfInvention | A novel process for preparing enalapril maleate |
abstract | The present invention relates to a method for preparing an enalapril maleate of general formula (I) which is useful for the treatment of hypertension, characterized by reacting the general formula (II), the general formula (III) and the general formula (IV) in a mixed solvent of water and acetone To a process for producing the same.n n n n n n n n Wherein R 1 and R 2 are Na or H. (Provided that R & lt ; 1 > and R & lt ; 2 >n n n Since the method of the present invention is characterized in that enalapril malate is synthesized in a first step reaction and crystals are obtained in water, unlike the prior art in which enalapril is synthesized after the synthesis of enalapril, It is simple, the synthesis time is shortened, the contamination problem is solved, and the cost is reduced, which is industrially useful. |
priorityDate | 1996-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.