| abstract |
Compounds of formula (1) or pharmaceutically acceptable salts thereof are selective autoreceptor agonists useful for treating disease states associated with overactivity of the dopamine system.n n n n n n n n Wherein X is-(CH 2 ) n , n is 1-3, R 1 is hydrogen, alkyl, hydroxyalkyl, cycloalkylmethyl, bicyclo-alkylmethyl or-(CH 2 ) m YAr, m is 0-4, Y is -CH 2- , Ar is phenyl, halophenyl, alkylphenyl, dialkylphenyl or alkoxyphenyl, R 2 is hydrogen or alkyl, R 3 is hydrogen, halogen, alkyl, Alkoxy or hydroxy. |