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filingDate 1994-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1996-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-960014129-A
titleOfInvention Cefem compound, preparation method thereof and use thereof for preparing cefem antibiotic
abstract 3-[(E) -1-propenyl] cepem compound of formula (I):n n n n n n n n [Wherein R represents a protecting group of hydrogen, an amino group or a group of the following general formula (II):n n n n n n n n {Wherein R 3 is a protecting group of an amino group, R 4 is a protecting group of a hydroxyl group, W is -CH = or -N =} R 22 is a protecting group of a carboxyl group; X 1 represents hydrogen or chlorine] This compound is useful as an intermediate for the preparation of cefem antibiotics and isomerizes the corresponding 3-[(Z) -1-propenyl] cepem compound in an inert organic solvent in the presence of an aromatic tee. It is prepared by making. Compounds of formula (I) wherein X is chlorine may be converted to 3- (E) -1-propenyl] cepem derivatives by reaction with tertiary amines.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100343662-B1
priorityDate 1993-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 38.