http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-960004359-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-067 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 |
| filingDate | 1994-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1996-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-960004359-A |
| titleOfInvention | Method for preparing 3'-azido-3'-deoxythymidine |
| abstract | The present invention provides a method for preparing 3′-azido-3′-deoxythymidine of the general formula (I) below, which is useful as an antiviral or AIDS treatment. In the process of the present invention, in preparing a compound of general formula (I) from thymidine, a hydroxyl group at the 5'-position is protected by a trityl group (compound of general formula (III ')) or an unprotected thymidine ( Reacting the compound of formula (III) with O-acetyl salicyloyl chloride to obtain a compound of formula (II) or formula (II ') below; Reacting a compound of formula (II) or formula (II ′) with (PhO) 2 PON 3 or Ph 3 P-NH 3 -diethyl azodicarboxylate; And if necessary, removing the protecting group of the hydroxyl group at the 5'-position.n n n n n n n n (The compound in which the 5′-position is -OR is (III ′).)n n n n n n n n (The compound whose 5′-position is -OR in the above formula is (II ′).)n n n n n n n n (Wherein R is a trityl group) |
| priorityDate | 1994-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.