http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-950029264-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 |
| filingDate | 1994-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1995-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-950029264-A |
| titleOfInvention | Method for preparing betamethylazetidinone derivative |
| abstract | The present invention is a method for preparing betamethylazetidinone derivatives, and more specifically, betamethylase of the following structural formula (II) used as an intermediate in the preparation of 1-betamethylcarbapenem antibiotic represented by the following structural formula (I): Thidinone derivatives, i.e. (3S, 4S) -3 (1R) -1 [(t-butyldimethylsilyl) oxy] ethylazin-4 '[(1R) -1-methyl- (4,4-dialkyl- 2-thioxo-1, 3-oxa or thiazolidin) -3-yl] methylpyazetidin-2-one.n n n n n n n n Wherein R represents an active residue having antibiotic activity, R 1 represents a t-butyldimethylsilyl group in a hydroxy protecting group, R 2 represents hydrogen or a lower alkyl group, X 1 and X 2 represent an oxygen or sulfur atom Indicates.n n n According to the present invention, the betamethylazetidinone derivative of the above formula (II) is obtained in high yield with high stereoselectivity, and provides a simple manufacturing method using achiral oxylary. |
| priorityDate | 1994-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.