http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-950029247-A

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C39-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-02
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C37-685
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C39-205
filingDate 1994-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1995-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-950029247-A
titleOfInvention Separation method of 5- (3- (2,4-dihydroxyphenyl) propyl) -3,4-bis (3-methyl-2-butenyl) -1,2-benzenediol and composition containing the same
abstract The present invention is a 5 (3 ((2, 4-dihydroxy phenyl) propyl))-3, 4-bis (3-methyl-2-part of bark (Broussonetia) plants and roots Tenyl) -1,2-benzenediol, and a method for separating and purifying the skin whitening composition, antioxidant composition and browning prevention composition containing the compound as an active ingredient. More specifically, extracting bark or root bark of the hawthorn plant with a polar solvent, concentrating the extract to obtain a concentrated extraction, and adding the fat-soluble solvent and water to the concentrated extract and partitioning the fat-soluble solvent layer fraction 5-(3-(2, 4-dihydroxyphenyl) propyl)-3, characterized in that it consists of a step of sequentially performing a Sephadex LH-20 column, a silica gin column and a reverse phase distribution column. 4) Bis (3 -methyl-2 -butenyl) -1, 2 -benzenediol separation and purification method and the compound obtained by the method to the tyrosinase activity inhibitory effect, antioxidant effect and polyphenol oxidase activity effective cosmetics, The invention is utilized in external skin preparations and food additives. The above compounds are excellent in inhibiting tyrosinase activity, sulfated effect, and polyphenol oxidase activity, so that they can be appropriately applied to cosmetics and external preparations for skin blackening and skin whitening. There is a significant effect on the inhibition of polyphenol oxidase activity on browning phenomenon due to oxidation.
priorityDate 1994-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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