| abstract |
The compounds of formula (I) below are suitable for the manufacture of a medicament for the prevention and treatment of diseases in response to the inhibition of osteoclast proton pumps.n n n n n n n n Wherein R 1 is hydroxy, 2-hydroxyethoxy, C 1 -C 4 alkoxy, C 1 -C 4 alkanoyloxy, halogen, amino, azido, keto, p-nitrobenzenesulfonyl or a general formula Pyranyloxy group (where X is or R 3 is hydroxy, C 1 -C 4 alkanoyloxy or organic sulfonyloxy, and R 4 is hydroxy, C 1 -C 4 alkanoyloxy or carbamoyloxy; R 2 is hydrogen, hydroperoxy, hydroxy or C 1 -C 4 alkoxy; Y is or Is a group wherein R 5 is hydroxy or C 1 -C 4 alkanoyloxy; R 6 and R 7 are each independently hydrogen or methyl. |