| abstract |
The present application is composed of microparticles having a nonionic surfactant, which is a surface modifier adsorbed on the surface, and a charged phospholipid, which is a point modifier associated with them, and a sufficient amount of a spot modifier to increase the cloud point of the surface modifier It provides a composition present. Preferred surfactants include poloxamine or tyloxapol, and preferred charged phospholipid cloud modifiers include dimyristoyl phosphatidyl glycerol.n n n The present application relates to a nonionic surfactant, which is a surface modifier adsorbed on a surface, and a cloud point modifier associated with them, which consist of contacting the microparticles with a cloud point modifier for a sufficient time under conditions sufficient to make the cloud point of the surface material critical It provides a method for producing microparticles having a phosphorus charge phospholipid. |