abstract |
The present invention relates to salts of compounds of the general formula (I), enantiomers, diastereomers, racemates and pharmaceutically acceptable bases thereof.n n n n n n n n Wherein R 1 is hydrogen, alkyl, cycloalkyl, carboxyl or alkoxycarbonyl, R 2 is hydrogen, halogen or alkyl, and A is structural formula Z and W are independently hydrogen or alkyl or together are alkylene, n is an integer from 0 to 1, m is an integer from 0 to 3, X is -CH 2 OH or -R 4 COR 5 , Y is halogen, alkoxy, acyloxy, hydroxy, alkyl, nitro, trifluoromethyl, hydrogen or cyano, R 3 is hydrogen, alkyl or cycloalkyl, R 4 is a direct bond, or CH 2 and R 5 is hydroxy, alkoxy, -NHR 6 or And R 6 is hydrogen or alkyl, R 7 and R 8 are independently hydrogen or alkyl or R 7 and R 8 together are alkylene, provided that m is 0 and n is 0, then R 1 or R One of three is cycloalkyl. |