| abstract |
Amino acid sequence; Homologs of fish GnRH with pGlu-His-Trp-Ser-Tyr-W-Trp-Leu-Arg-Pro-Gly-X-Y-Z are described.n n n Wherein W represents Gly or D-amino acid, X represents one or more amino acids which may be bonded or the same or different, Y represents or does not exist Cys or Tyr and Z may be absent or the same or different Present amino acids, or continuous or discontinuous peptide chains, discontinuous or each discontinuous represents a non-a amino acid multifunctional linker residue or a retro-inverso amino acid, provided that W- is Gly and X and Y are absent Z is present. This homologue can be conjugated with a carrier and used, for example, to delay sexual maturity and onset of growth. |