| abstract |
The present invention relates to a medicament containing a vinyl azole of the following general formula (I) and a novel vinyl azole of the general formula (Ia) contained in the scope of the general formula (I).n n n n n n n n In the above formulas, the substituents X, Y, Z, R 1 , R 2 and R 3 or Z a and R 2a are as defined above.n n n The compounds of formula (I) or (Ia) are effective as inhibitors of estrogen biosynthesis (aromatase inhibitors) and are either estrogen-induced or are suitable for the treatment of estrogen-dependent diseases.n n n The present invention also relates to a process for preparing a compound of formula (I). |