abstract |
The present invention relates to an antiviral agent and antineoplastic agent containing a compound represented by the following general formula (1) and a salt thereof as well as a compound represented by the general formula (1) as an active ingredient.n n n n n n n n X is OH, a methyl group, a sulfhydryl, a C1-6 monoalkylamino group, Y and Z are each 0 or 1, and m is 0 or 1, n is 4 to 29, represents a S atom, R 1, R 2 and R 3 are the same or may be different and each H, C 1 ~ 4 alkoxy group, or a C 1-6 alkyl group, or a substituent Group in any represents a substituted aryl of C 6 ~ 10 D, and B respectively to the selected substituent from the is a substituent group β residues from the group independently selected from the below (where, k = 0 when, m = - a, B Is a nucleotide sequence complementary to a tumor gene or a virus gene);n n n Substituent n n n OH, alkoxy, methylene-dioxide group of C 1 ~ 6 alkyl group, C 1 ~ 6, the nitro group, azide group, halogen atom, C aryl group of 6 ~ 10, C 6 ~ 10 aryl part and a C 1 ~ An aralkyloxy group having 2- alkyl moiety,n n n Substituent?n n n Adenine, guanine, cytosine and thymine, |