| abstract |
The present invention relates to compounds of formula (I) or (II), and physiologically acceptable salts thereof.n n n n n n n n Wherein R is a hydrogen atom or a lower alkyl group, Y and Z are the same or different and independently an alkylene group having 2 to 5 carbon atoms in the alkylene chain, which may be substituted by lower alkyl, and X is a single bond Or an alkylene group having 1 to 10 carbon atoms in the alkylene chain, which may be substituted with lower alkyl, AO- is a compound moiety with estrogen activity, and q is an integer of 1 to 3.n n n The compounds of formula (I) or formula (II) are useful as inhibitors of bone absorption and therapeutic agents for bone diseases. |