| abstract |
Provided herein are scaffold biomaterials comprising decellularized plant or hyphal tissue from which cellular substances and nucleic acids of the tissue have been removed, wherein the decellularized plant or hyphal tissue has a three-dimensional porous structure, wherein the decellularized The plant or hyphal tissue may optionally be at least partially coated or mineralized, and the scaffold biomaterial may optionally further comprise a protein-based hydrogel and/or a polysaccharide-based hydrogel, or both. Also provided herein are methods of making and using such scaffold biomaterials, including, for example, methods of making as well as methods of making and using for bone tissue engineering. |