| abstract |
The present invention relates to a composition for preventing or treating autoimmune diseases comprising mitochondria as an active ingredient, wherein the composition according to the present invention relieves osteoarthritis pain and alleviates symptoms, reduces joint damage, and promotes differentiation of chondrocytes It can effectively prevent and treat osteoarthritis by inhibiting inflammatory cell death of cartilage cells. In addition, the muscle-derived mitochondria in the present invention have the ability to regulate inflammatory cytokines and Treg/Th17 cells in the osteoarthritis animal model, encephalomyelitis model, Sjogren's syndrome animal model, and transplant rejection model, which can be used for various inflammatory diseases or immune diseases. . |