| abstract |
Recombinant nucleic acid constructs encoding chemokines, cytokines, or apoptosis inducing proteins (eg, caspase 9 (Casp9)), or other toxins in a form that can only be transcribed in the presence of viral polymerase or replication-deficient virus - Methods and compositions using the like particles are provided. These methods can be tailored to target many viral infections, reduce or eliminate the viral load, and provide radically different treatments for viral infections. |