http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220081913-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_050fc7b82c5d17d9aeb63a7cdcc546b3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 |
| filingDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5996dc64296b0816c33ceb73afe8f8c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad6869a0356531ec9ae37f3bc4df5588 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec09419ef565f828bef198b835967847 |
| publicationDate | 2022-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20220081913-A |
| titleOfInvention | A composition for regulating NK cell activity comprising TSAHC or a pharmaceutically acceptable salts thereof as an active ingredient |
| abstract | The present invention relates to a composition for regulating immune cell activity comprising 4'-(p-toluenesulfonylamino)-4-hydroxychalcone or a pharmaceutically acceptable salt thereof as an active ingredient, wherein TM4SF5 is inhibited by TSAHC treatment As a result, it was confirmed that the population of NK cells present in the spleen is increased, the expression of NK cell activating ligands in hepatic epithelial cells is increased, and ultimately the cytotoxic activity of NK cells is increased, 4'-(p- A composition comprising toluenesulfonylamino)-4-hydroxychalcone or a pharmaceutically acceptable salt thereof as an active ingredient may be usefully used as an NK cell activity modulator. |
| priorityDate | 2020-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 264.