abstract |
The present invention relates to a fusion protein comprising a mutant IL-15 protein, a fusion protein comprising a mutant anti-PD-1 antigen binding domain, and a fusion protein comprising a mutant IL-15 protein and a mutant anti-PD-1 antigen binding domain will be. The present invention also relates to nucleic acid molecules, expression vectors, host cells, and methods of making such fusion proteins and the use of such fusion proteins in the treatment of cancer. |