| abstract |
Biomaterials (mammalian, plant-based, synthetically derived, or microbially derived) is described. The bio-ink composition has excellent printability and improved cell function, viability and engraftment. In addition, the bio-ink composition can be supplemented via growth factors and morphogenetic sources, including additional accessory proteins and other molecules such as extracellular matrix components, laminins, super-affinity growth factors. The bio-ink composition can be used under physiological conditions related to cytocompatibility 3D bioprinting parameters (eg temperature, printing pressure, nozzle size, bio-ink gelation process). Combination of biogum-based biomaterials with mammalian, plant, microbial or synthetically derived hydrogels provides improvements in printability, cellular function and viability compared to tissues printed with bioinks that do not contain biogums. indicated. |